Sorafenib CAS NO.284461-73-0 CAS NO.284461-73-0

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Product Name:	Sorafenib tosylate
Synonyms:	sorafenib;SORAFENIB-D3;SORAFENIB TOLSYLATE;RAF1 KINASE INHIBITOR II;N-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)-((4-(2-(N-METHYL-CARBAMOYL)(4-PYRIDYLOXY))PHENYL)AMINO)CARBOXAMIDE;4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-n-methyl-pyridine-2-carboxamide;BAY 43-9006;SORAFENIB MESYLATE
CAS:	284461-73-0
MF:	C21H16ClF3N4O3
MW:	464.83
EINECS:
Product Categories:	Sorafinib;Molecular Targeted Antineoplastic;All Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;Amines;Inhibitor;Bay 43-9006
Mol File:	284461-73-0.mol

Sorafenib tosylate Chemical Properties

Safety Information

MSDS Information

Sorafenib tosylate Usage And Synthesis

Chemical Properties	Light Yellow Solid
Usage	A potent RAF kinase inhibitor. Antineoplastic
Usage	Multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
Usage	Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively.
Usage	Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively - See more at: #